Sodium, Na

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Tissue Sodium Na Magnetic Resonance Imaging of Tissue Sodium

Hypertension is linked to disturbed total-body sodium (Na ) regulation; however, measuring Na disposition in the body is difficult. We implemented Na magnetic resonance spectroscopy (Na-MR) and imaging technique (Na-MRI) at 9.4T for animals and 3T for humans to quantify Na content in skeletal muscle and skin. We compared Na-MRI data with actual tissue Na content measured by chemical analysis in...

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Sodium (Na) MR Imaging in Pediatric Astrocytomas

Figure 2. (above) Na Averages in Pediatric Brains. Sodium (Na) MR Imaging in Pediatric Astrocytomas Vincent Kyu Lee, Rafael Ceschin, Yongxian Qian, Fernando Boada, James Mountz, Regina Jakacki, Ian Pollack, and Ashok Panigrahy Radiology, University of Pittsburgh, Pittsburgh, Pa, United States, Radiology, University of Pittsburgh, Pa, United States, Bioengineering, University of Pittsburgh, Pa, ...

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Physiological interactions between Na(v)1.7 and Na(v)1.8 sodium channels: a computer simulation study.

We have examined the question of how the level of expression of sodium channel Na(v)1.8 affects the function of dorsal root ganglion (DRG) neurons that also express Na(v)1.7 channels and, conversely, how the level of expression of sodium channel Na(v)1.7 affects the function of DRG neurons that also express Na(v)1.8, using computer simulations. Our results demonstrate several previously undescr...

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Catalysis of Na+ permeation in the bacterial sodium channel Na(V)Ab.

Determination of a high-resolution 3D structure of voltage-gated sodium channel Na(V)Ab opens the way to elucidating the mechanism of ion conductance and selectivity. To examine permeation of Na(+) through the selectivity filter of the channel, we performed large-scale molecular dynamics simulations of Na(V)Ab in an explicit, hydrated lipid bilayer at 0 mV in 150 mM NaCl, for a total simulation...

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Gating properties of Na(v)1.7 and Na(v)1.8 peripheral nerve sodium channels.

Several distinct components of voltage-gated sodium current have been recorded from native dorsal root ganglion (DRG) neurons that display differences in gating and pharmacology. This study compares the electrophysiological properties of two peripheral nerve sodium channels that are expressed selectively in DRG neurons (Na(v)1.7 and Na(v)1.8). Recombinant Na(v)1.7 and Na(v)1.8 sodium channels w...

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ژورنال

عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan

سال: 1989

ISSN: 0037-9980,1883-6526

DOI: 10.5059/yukigoseikyokaishi.47.669